by and large   (TTS發音)

on the whole；in general 總的說來；大體上說

    By and large，your suggestion is a good one. 總的說來，你的建議是好的。

    By and large，you'll live longer if you try to be more easygoing about life. 大體上可以說，如果你對待生活能寬容隨和的話，你就會活得長一些。